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1221

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1221

1100–1532South America [administration]The Inca empire dominates the Andes region of South America. Its population numbers as many as 12 million. Incan society is based on a strict hierarchy, with an emperor who rules with absolute power. Their religion is based on sun-worship, and they are skilled builders who create a system of roads and irrigation.
c. 1200–c. 1230South America [political events]Manco Capac founds the Inca state in the Cuzco Valley, Peru.
1202–1304Flanders [civic and commercial buildings]The Cloth Hall at Ypres, in Flanders (now part of Belgium), one of the finest Gothic secular buildings of the late Middle Ages, is built. It is destroyed in 1915.
8 August 1221Ayyubid Sultanate, Egypt, Italy, Scandinavia, Austria, Germany, Flanders [Crusades (1095–1272)]The army of the Fifth Crusade, advancing into Egypt from Damietta, is trapped by the Nile floods and the Egyptian army; the leader of the crusade, Cardinal Pelagius, is forced to accept Sultan al-Kamil of Egypt's terms for withdrawal, including the surrender of Damietta.
24 November 1221Khwarizm, Mongol Empire, India, Delhi Sultanate [Mongol conquests (1206–1405)]The shah of the central Asian province of Khwarizm, Jalal-ad-Din, defeats the Mongols under Kutikonian at Parvan (near modern Kabul, Afghanistan). The Mongol leader Genghis Khan quickly avenges the defeat, destroying Jalal-ad-Din's army at Bamian (in present-day Afghanistan); Jalal-ad-Din flees to India with the Mongols in pursuit. After defeating Jalal-ad-Din again on the River Indus, Genghis Khan withdraws his forces to avoid war with the Sultanate of Delhi.


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The deal comes less than a month after Morgan Stanley leased 600,000 s/f at 522 Fifth Avenue to house operations for its growing asset management group, an arm of the financial giant's business that focuses primarily on mutual fund management and wealth management for ultra high net worth individuals and that currently occupies 10 floors at 1221 Avenue of the Americas.
In this study we examined the endocrine-disrupting effects of Aroclor 1221 (a commercial PCB mixture), focusing on its actions on the ER-[beta], which has been implicated in mediating effects of endocrine-disrupting chemicals.
The 1221 program can be difficult to complete unless the manufacturer keeps that specification in mind when designing the product.
 
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