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309| 200–700 | Central America [statistics and demography] | The Zapotec site of Monte Albán in Central America is at its peak in this period. It may have had 30,000 or more inhabitants. It is the centre of a complex of public buildings, temples, and dwellings that cover 40 sq km/15 sq mi. | | 309 | Roman Empire [plagues and epidemics] | A plague that may be related to anthrax spreads across the Roman Empire, causing a drastic decline in the population. |
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