4-hydroxytamoxifen - Hutchinson encyclopedia article about 4-hydroxytamoxifen Printer Friendly
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tamoxifen
(redirected from 4-hydroxytamoxifen)

    Also found in: Medical, Encyclopedia, Wikipedia 0.02 sec.

tamoxifen

Oestrogen-blocking drug used to treat breast cancer and also infertility. It kills cancer cells by preventing formation of the tiny blood vessels that supply the tumour. Without a blood supply the tumour shrinks as its cells die. Side effects include hot flushes, skin rashes, vaginal discharge, and more rarely, endometrial cancer. Trials have shown that it may also prevent breast cancer in healthy women with a family history of the disease.



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? Mentioned in ? References in periodicals archive
 
There is also "compelling evidence" that the drug's active metabolite in the body -- 4-hydroxytamoxifen -- stimulates the growth of human endometrial cancer cells grown in culture, notes Liam J.
Tamoxifen quandary; promising cancer drug may hide a troubling dark ... by Raloff, Janet / Science News
The use of the innovative EHG(TM) technology as a delivery vehicle for 4-hydroxytamoxifen has enabled the clinical development of this promising, but previously undeveloped molecule, now in Phase II trials.
ASCEND Therapeutics, Inc. Acquires North American Product Rights; New ... by Business Wire
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