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dwarfism
(redirected from Achrondroplasia)

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dwarfism

Abnormally short stature. The most common form is achondroplasia an inherited disorder in which the limbs fail to reach a normal length. The achondroplastic dwarf has short limbs but a head and trunk of normal size.

In pituitary dwarfism there is a deficiency of growth hormone; the pituitary dwarf is physically well proportioned but may be sexually underdeveloped. Intelligence is not affected.

Approximately 90% of achondroplasia cases occur where there is no family history, as a result of a mutation on chromosome 4. The fathers of these children tend to be older than average. The mutation is a dominant trait so it will be passed on to any children.



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Sex Delivery outcome m f Polydactyly 50 25 Talipes 12 12 Genurecurvatum 04 05 Achrondroplasia 06 00 Intra-uterine amputation 01 02 (amniotic bands) 02 Syndactyly 02 01 Craniovertebral anomaly 01 00 Amelia upper limbs 01 00 Osteogenesis imperfects 00 00 Hypoplastic femur 00 01 Hypoplastic mandible (severe) 00 01 Oxycephaly 00 01 N 79 48 rate per Delivery outcome 1000 births freq Polydactyly 10.
 
 
 
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