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aluminium hydroxide
(redirected from Alhydrogel)

   Also found in: Wikipedia 0.04 sec.

aluminium hydroxide

Gelatinous precipitate formed when a small amount of alkali solution is added to a solution of an aluminium salt.

Al3+(aq) OH(aq) → Al(OH)3(s)

It is an amphoteric compound as it readily reacts with both acids and alkalis.



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While aluminum salt (alum) derivatives such as Alhydrogel are the only adjuvants currently approved by the FDA, they have has been associated with adverse reactions such as irritation and inflammation of the injection site, and may also result in an allergic reaction.
BioSante is responsible for developing formulations of BioVant with the anthrax vaccine antigens and will conduct immunization studies in animals to determine the immunogenicity of the resulting BioVant/antigen vaccines compared with an anthrax vaccine formulated with Alhydrogel.
 
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