Aminoglycosides - Hutchinson encyclopedia article about Aminoglycosides Printer Friendly
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aminoglycoside
(redirected from Aminoglycosides)

   Also found in: Medical, Wikipedia 0.23 sec.

aminoglycoside

Any of a group of antibiotics, including gentamicin, neomycin, and streptomycin, that are effective against a wide range of bacteria. As they are not absorbed from the intestine, they are usually given by injection. Drugs in this group are quite toxic, with side effects including damage to the ears and kidneys. For this reason they are only used for infections that do not respond to other antibiotics.



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When testing Enterococcus faecalis isolates harboring any of the clinically observed resistance, including resistance to beta-lactams, glycoproteins or aminoglycosides, ceftobiprole showed excellent in vitro bactericidal activity.
The antibiogram, which was performed by a disk diffusion method, showed AX476 to be highly resistant to ceftazidime, aminoglycosides, sulfonamides, trimethoprim, and ciprofloxacin but fully susceptible to tetracyclines, piperacillin/tazobactam, ticarcillin/clavulanic acid, and imipenem.
(3) Quinolones have largely replaced the aminoglycosides as a topical therapy for keratitis during the past 10 years, and they are largely successful.
 
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