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aniline
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   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.

aniline

One of the simplest aromatic chemicals (a substance related to benzene, with its carbon atoms joined in a ring). When pure, it is a colourless oily liquid; it has a characteristic odour, and turns brown on contact with air. It occurs in coal tar, and is used in the rubber industry and to make drugs and dyes. It is highly poisonous.

Aniline was discovered in 1826, and was originally prepared by the dry distillation of indigo, hence its name. In the 19th century, the production of aniline-based dyes was a key industry.



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? Mentioned in ? References in periodicals archive
 
High temperatures and extreme vacuum conditions during the refining process led to a reaction of the aniline with fatty acids and tryglicerides, which are basic in regular oils, producing two different new families of compounds: fatty acid anilides and esters of the phenyl amino propanediol.
14 Issue 1), the Company describes its recent progress in the development of HDAC inhibitors for oncology, which includes hydroxamic acids, anilides, TSA-like straight chain derivatives, and 2-aminophenylamides of omega-substituted alkanoic acids.
Despite the analytical efforts seeking toxic substances in these oils, only aniline derivatives such as fatty acid anilides (1,3,17,18) and fatty acid esters of 3-phenylamino-1, 2-propanediol (PAP esters) (19-21) have been identified in toxic oil batches.
 
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