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antigen |
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antigenAny substance that causes the production of antibodies by the body's immune system. Common antigens include the proteins carried on the surface of bacteria, viruses, and pollen grains. The proteins of incompatible blood groups or tissues also act as antigens, which has to be taken into account in medical procedures such as blood transfusions and organ transplants. |
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Dendritic cells are known to be important in antigen presentation and in determining the nature of subsequent immune responses. Interferon appears to be an excellent adjuvant that enhances production of immunoglobulins and contributes to the activation of dendritic cells required for antigen presentation (21-23). Faustman and her colleagues have found that, in an inbred strain of mice prone to diabetes, defects in a cellular structure called the proteosome can prevent female cells from chopping up proteins as required for antigen presentation. |
Antigen presentation
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