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protease
(redirected from Aspartic protease)

    Also found in: Medical, Encyclopedia, Wikipedia 0.02 sec.

protease

General term for an enzyme capable of splitting proteins. Examples include the digestive proteases pepsin, found in the stomach, and trypsin, found in the small intestine.

Proteases are also found within cells, for example the proteasome, which removes damaged proteins. The AIDS virus, HIV, carries a gene for its own protease, which is vital for its function and hence serves as a target for certain AIDS drugs.



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? Mentioned in ? References in periodicals archive
 
We compared phenotypic markers of pathogenesis, including adherence, biofilm formation, and protein secretion (secretory aspartic protease [SAP] and phospholipase).
Candida parapsilosis characterization in an outbreak setting by Ghannoum, Mahmoud A. / Emerging Infectious Diseases
He applied these techniques to the design of compounds in a number of therapeutic areas, including aspartic protease inhibitors.
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One of these proteases (Histidine Aspartic Protease, HAP) is homologous to three other aspartic proteases involved in hemoglobin metabolism but has a histidine in place of one of the two aspartic acids involved in catalysis.
Fifth annual Conference on New and Re-Emerging Infectious Diseases. ... by Docampo, Roberto / Emerging Infectious Diseases
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