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protease
(redirected from Aspartic protease)

    Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.

protease

General term for an enzyme capable of splitting proteins. Examples include the digestive proteases pepsin, found in the stomach, and trypsin, found in the small intestine.

Proteases are also found within cells, for example the proteasome, which removes damaged proteins. The AIDS virus, HIV, carries a gene for its own protease, which is vital for its function and hence serves as a target for certain AIDS drugs.



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? Mentioned in ? References in periodicals archive
 
A synergy effect has been occurred when mixtures of cysteine and aspartic protease inhibitors were treated to control malarial parasite, P.
Antimalarial activity of anthothecol derived from Khaya anthotheca ... by Lee, Sung-Eun; Kim, Mi-Ran; Kim, Jeong-Han; Takeoka, Gary R.; Kim, Tae-Wan; Park, Byeoung-Soo / Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
Aspartic Protease, HAP) is homologous to three other aspartic proteases involved in hemoglobin metabolism but has a histidine in place of one of the two aspartic acids involved in catalysis.
Fifth annual Conference on New and Re-Emerging Infectious Diseases. ... by Docampo, Roberto / Emerging Infectious Diseases
The company has two fundamental technology platforms: (i) aspartic protease inhibitors, including beta-secretase inhibitors for Alzheimer's disease; and (ii) nicotinic acetylcholine receptor (nAChR) agonists and antagonists for the treatment of angiogenesis mediated diseases and cognitive disorders.
JDRF Partners with CoMentis for Diabetic Macular Edema Clinical Trial by Business Wire
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