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base pair
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base pair

In biochemistry, the linkage of two base (purine or pyrimidine) molecules that join the complementary strands of DNA. Adenine forms a base pair with thymine (or uracil in RNA) and cytosine pairs with guanine in a double-stranded nucleic acid molecule.

One base lies on one strand of the DNA double helix and one on the other, so that the base pairs link the two strands like the rungs of a ladder. In DNA, there are four bases: adenine and guanine (purines) and cytosine and thymine (pyrimidines). Adenine always pairs with thymine and cytosine with guanine.

The sizes of genes and genomes are commonly cited in base pairs, for example the human genome consists of around 3 billion base pairs.



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? Mentioned in ? References in periodicals archive
 
It is incorporated by reverse transcriptase, and once it's incorporated, just as the transcription process would dictate, there is base-pair matching that goes on.
New kind of antiretroviral, KP-1461; clinical trial recruiting. ... by James, John S. / AIDS Treatment News
Buckle warns, however, that while this mapping technique can provide resolution in the thousand base-pair (kilobase) range, confirming that level of detail will require much added work.
Now in vivid color, details of DNA by Pennsi, Elizabeth / Science News
The DNA portion recognizes the base-pair sequence of the target RNA, and the RNA part breaks the sequence apart, explains John J.
...And in the form of catalytic RNA by Pennisi, Elizabeth / Science News
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