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cartilage |
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cartilageFlexible bluish-white connective tissue made up of the protein collagen. In cartilaginous fish it forms the skeleton; in other vertebrates it forms the greater part of the embryonic skeleton, and is replaced by bone in the course of development, except in areas of wear such as bone endings, and the discs between the backbones. It also forms structural tissue in the larynx, nose, and external ear of mammals. Cartilage does not heal itself, so where injury is severe the joint may need to be replaced surgically. In a 1994 trial, Swedish doctors repaired damaged knee joints by implanting cells cultured from the patient's own cartilage. In 1999 US chemists created an artificial liquid cartilage for use in repairing torn tissue. The cartilage is injected into a wound or damaged joint and will harden with exposure to ultraviolet light. Clinical trials commenced in 2000. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Discovered in 1998, CILP had been implicated in osteoarthritis and some other degenerative cartilage diseases. The business model in Nordic Bioscience A/S is based on the synergy created by integrating diagnostic and therapeutic research within certain disease areas - primarily bone diseases such as osteoporosis and bone metastasis, but also cartilage diseases as osteoarthritis and rheumatoid arthritis. The lead compound, NBS 101, belongs to a new class of drugs for treatment of osteoporosis, and other bone and cartilage diseases. |
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