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cell membrane |
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cell membrane![]() Typical plant and animal cell. Plant and animal cells share many structures, such as ribosomes, mitochondria, and chromosomes, but they also have notable differences: plant cells have chloroplasts, a large vacuole, and a cellulose cell wall. Animal cells do not have a rigid cell wall but have an outside cell membrane only. Thin layer of protein and fat surrounding cells that keeps the cells together and controls substances passing between the cytoplasm and the intercellular space. The cell membrane is semipermeable, allowing some substances to pass through and some not. Generally, small molecules such as water, glucose, and amino acids can penetrate the membrane, while large molecules, such as starch, cannot. Substances often cross the membrane by diffusion, a spontaneous passage of molecules. Water movement across the membrane is a special case of diffusion known as osmosis. Membranes also play a part in active transport, hormonal response (see hormones), and cell metabolism. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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In a cellular membrane, the water-attracting groups, which are exposed to the aqueous cellular environment, sandwich an inner core of water-repelling tails. Lipid damage in the cellular membrane then leads to calcium leakage from internal sites in the cell, triggering the second step: an increase in the synthesis of the free radical nitric oxide. Agents like pentafuside (T-20) and its likely successor, T-1249, act by interfering with the so-called "hairpin" mechanism of one of HIV's proteins, which unfolds in a hinged fashion, extends itself to harpoon the cell membrane and then coils back onto itself to bring the virus close to the cellular membrane. |
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