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cephalosporin |
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cephalosporinAny of a class of broad-spectrum antibiotics derived from a fungus (genus Cephalosporium). They are similar to penicillins and are used on penicillin-resistant infections. The first cephalosporin was extracted from sewage-contaminated water, and other naturally occurring ones have been isolated from moulds taken from soil samples. Side effects include allergic reactions and digestive upsets. Synthetic cephalosporins can be designed to be effective against a particular pathogen. |
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| In three separate surveillance studies (E-0112, E-0115, E-0117) ceftobiprole was amongst the most potent cephalosporins against Enterobacteriaceae and Pseudomonas -- the most common Gram-negative bacterial pathogens associated with hospital-acquired infections -- explained in part by its enhanced affinity for the penicillin-binding protein 2 (PBP2) in pseudomonads (C1-0933). Cephalosporins in particular seemed to provide adequate antibiotic coverage. Cows were treated for lameness with primarily beta-lactams, cephalosporins and tetracylines. |
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