Chronic thromboembolic disease - Hutchinson encyclopedia article about Chronic thromboembolic disease Printer Friendly
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thrombosis
(redirected from Chronic thromboembolic disease)

    Also found in: Medical, Encyclopedia, Wikipedia 0.07 sec.

thrombosis

Condition in which a blood clot forms in a vein or artery, causing loss of circulation to the area served by the vessel. If it breaks away, it often travels to the lungs, causing pulmonary embolism.

Thrombosis in veins of the legs is often seen in association with phlebitis, and in arteries with atheroma. Thrombosis increases the risk of heart attack and stroke. It is treated by surgery and/or anticoagulant drugs.

According to 1996 figures, in the USA 5.5 million people suffer from thrombosis and about 100,000 die of pulmonary embolism annually.



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In patients with chronic thromboembolic disease and large central clots, pulmonary endarterectomy can prevent further propagation of changes in patent vessels, improve ventilation-perfusion mismatch, and limit right ventricular dysfunction, tricuspid regurgitation and extension of clot.
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ARIES-3 will enroll up to 200 patients in PH subgroups, including: PH associated with interstitial lung disease (ILD); PH due to chronic thromboembolic disease or sickle cell disease; PH associated with chronic obstructive pulmonary disease (COPD); PAH associated with congenital heart defects; and PAH associated with HIV infection.
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