Ciclosporin - Hutchinson encyclopedia article about Ciclosporin Printer Friendly
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cyclosporin
(redirected from Ciclosporin)

    Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia 0.01 sec.

cyclosporin

Immunosuppressive drug derived from a fungus (Tolypocladium inflatum). In use by 1978, it revolutionized transplant surgery by reducing the incidence and severity of rejection of donor organs.

It suppresses the T-cells (see lymphocyte) that reject foreign tissue without suppressing other cells that fight infection and cancer.



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? Mentioned in ? References in periodicals archive
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Renal toxicity of long-term ciclosporin Scand J Rheumatol 1999;28:65-8.
Principles of the treatment of psoriasis and therapeutic ... by Onsun, Nahide / Archives of the Turkish Dermatology and Venerology
Oral treatment with immunosuppressants such as ciclosporin (Neoral), or methotrexate (eg Maxtrex) or the vitamin A derivative acitretin (Neotigason) may be used for patients with severe, widespread or unresponsive psoriasis.
Pustular Psoriasis Facts and Treatment by Francis Adam / Health, general community
Grapefruit juice should also be avoided if you take ciclosporin, terfenadine, vardenafil or sirolimus.
Patients warned of juice side-effects by Evening Gazette (Middlesbrough, England)
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