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cosmid
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   Also found in: Medical, Wikipedia 0.01 sec.

cosmid

Fragment of DNA, for example from the human genome, inserted into a bacterial cell. The bacterium replicates the fragment along with its own DNA. In this way the fragments are copied for a gene library. Cosmids are characteristically 40,000 base pairs in length. The most commonly used bacterium is Escherichia coli. A yeast artificial chromosome (YAC) works in the same way.



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Afterwards, randomly selected cosmids, the so called seed clones, were sequenced up to publication quality.
CosMCPrep eliminates this problem, enabling the efficient, fully-automated purification of low copy plasmids such as BACs, cosmids and fosmids.
Phrap was originally developed with a more narrow focus as a tool to assist genome centers sequencing cosmids," stated Dr.
 
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