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lymphocyte
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lymphocyte

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B cells, a type of lymphocyte (white blood cell), have an important role in the body's immune system. When a B cell encounters an invading bacterium it starts to divide, forming two different types of cell. One type is a clone of itself that begins to produce antibodies to fight the infection; the other is a memory cell that will persist in the bloodstream, ready to produce antibodies should re-infection occur.
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T cells, a type of lymphocyte (white blood cell), have an important role in the body's immune system. When a T cell encounters an invading virus it begins to divide, forming four different types of T cell, each with a different function. Killer T cells destroy cells that have become infected with the virus by lysis. Helper T cells activate more killer T cells and also stimulate B cells to begin antibody production (unlike B cells, T cells do not produce antibodies to destroy invading pathogens). Suppressor T cells protect healthy cells from viral attack and memory T cells persist in the bloodstream to guard against re-infection.

Type of white blood cell with a large nucleus, produced in the bone marrow. Most occur in the lymph and blood, and around sites of infection. B lymphocytes or B cells are responsible for producing antibodies. T lymphocytes or T cells have several roles in the mechanism of immunity.


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The most important effectors of the cell-mediated immune response, cytotoxic T lymphocytes, are the main immune cells that recognize foreign antigens on the surface of infected "self" cells.
These approaches include biologic therapy using interleukin (IL)-2, IL-12, interferon-alpha, monoclonal antibodies directed against B cell targets, cytotoxic T lymphocytes directed against viral targets, immune-based therapy, stem cell reconstitution, angiogenesis inhibitors, therapeutic vaccines, and traditional cytotoxic chemotherapy regimens (often in combination with a biologic or immunologic approach).
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia.
 
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