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thalidomide
(redirected from Distaval)

    Also found in: Medical, Encyclopedia, Wikipedia 0.02 sec.

thalidomide

Hypnotic drug developed in the 1950s for use as a sedative. When taken in early pregnancy, it caused malformation of the fetus (such as abnormalities in the limbs) in over 5,000 recognized cases, and the drug was withdrawn.

In 1995 US researchers announced trials using thalidomide derivatives for a variety of immune disorders, including AIDS, cancer, and graft-versus-host disease – it was already used routinely in the treatment of leprosy. In 1997 it was approved for that purpose by the US Food and Drug Administration.



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? Mentioned in ? References in periodicals archive
 
In Britain the most commonly prescribed drug containing Thalidomide was Distaval, manufactured by the Distillers Company and was taken off the market in 1961 and banned the following year.
12,000 babies born deformed; new you by South Wales Echo (Cardiff, Wales)
Thalidomide, sold under brands names including Contergan and Distaval, was first made by privately owned German group Grunenthal and marketed internationally to pregnant women.
Thalidomide victims seek compensation, 50 years on by Adverse Event Reporting News
Louise was one of the first 'thalidomide babies' - she was born in 1962 without arms or legs as a result of my wife taking Distaval sleeping pills containing thalidomide for one week near the start of her pregnancy.
BACK INTO BATTLE FOR LOUISE; Thirty years ago I fought for my ... by The Daily Mail (London, England)
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