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thalidomide
(redirected from Distaval)

   Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia 0.02 sec.

thalidomide

Hypnotic drug developed in the 1950s for use as a sedative. When taken in early pregnancy, it caused malformation of the fetus (such as abnormalities in the limbs) in over 5,000 recognized cases, and the drug was withdrawn.

In 1995 US researchers announced trials using thalidomide derivatives for a variety of immune disorders, including AIDS, cancer, and graft-versus-host disease – it was already used routinely in the treatment of leprosy. In 1997 it was approved for that purpose by the US Food and Drug Administration.



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In Britain the most commonly prescribed drug containing Thalidomide was Distaval, manufactured by the Distillers Company and was taken off the market in 1961 and banned the following year.
Thalidomide, sold under brands names including Contergan and Distaval, was first made by privately owned German group Grunenthal and marketed internationally to pregnant women.
More than 40 years after the medication, known as Distaval, left hundreds of babies in Britain with missing or deformed limbs, the food and drink giant Diageo has caved in to pressure to increase the fund that now supports sufferers.
 
 
 
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