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Fenn, John B

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Fenn, John B (1917– )

US analytical chemist who was awarded the 2002 Nobel Prize for Chemistry (with Japanese engineer Koichi Tanaka and Swiss structural biologist Kurt Wüthrich) for his development of soft desorption methods for mass spectrometric analysis of biological macromolecules.

Fenn developed methods to allow the analysis of biological macromolecules, such as proteins, using the important analytical technique of mass spectroscopy. Previous to this work, only small fragments could be identified using this technique. Fenn also developed electrospray ionisation (ESI) which has important applications such as the study and diagnosis of breast and prostate cancer.

Since 1994, Fenn has been Research Professor at Virginia Commonwealth University, in Richmond, Virginia.



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