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prostacyclin
(redirected from Flolan)

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prostacyclin

In medicine, a prostaglandin that is produced by the endothelial lining of the blood vessels. It inhibits the aggregation of platelets in the cardiovascular system and, consequently, the formation of blood clots. It is also a potent vasodilator, causing blood vessels to dilate.

Prostacyclin, either alone or in combination with heparin, is used to inhibit platelet aggregation in patients undergoing renal dialysis. It has to be given by continuous intravenous infusion because its half-life is only three minutes. Adverse effects include flushing, hypotension, and headache because of its activity as a vasodilator.
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Across the Atlantic, the US Food & Drug Administration approved Teva Pharmaceutical's application to market its rival generic version of GlaxoSmithKline's drug Flolan.
Major contract boosts Chieftain; Stocks and shares by The Journal (Newcastle, England)
Continuous intravenous dobutamine is associated with an increased risk of death in patients with advanced heart failure: Insights from the Flolan International Randomized Survival Trial (FIRST).
Effect of intravenous positive inotropic therapy on myocardial damage ... by Albayrak, Fulya; Demircan, Sabri; Yazici, Mustafa; Arslandag, Muharrem / The Anatolian Journal of Cardiology (Anadolu Kardiyoloji Dergisi)
Other services provided by Accredo for patients receiving Flolan includes benefit coordination, patient education, prescriber support, and product dispensing and compliance management.
ACCREDO SIGNS 5-YEAR SPECIALTY PHARMACY PACT FOR FLOLAN by Biotech Business
 
 
 
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