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prostacyclin
(redirected from Flolan)

    Also found in: Medical, Wikipedia 0.54 sec.

prostacyclin

In medicine, a prostaglandin that is produced by the endothelial lining of the blood vessels. It inhibits the aggregation of platelets in the cardiovascular system and, consequently, the formation of blood clots. It is also a potent vasodilator, causing blood vessels to dilate.

Prostacyclin, either alone or in combination with heparin, is used to inhibit platelet aggregation in patients undergoing renal dialysis. It has to be given by continuous intravenous infusion because its half-life is only three minutes. Adverse effects include flushing, hypotension, and headache because of its activity as a vasodilator.



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Myogen is a big player in PAH already with Flolan, but could really capture big market share in the category once phase III product ambrisentan comes to market.
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Flolan was approved in 1995 and is indicated for the long-term intravenous treatment of primary pulmonary hypertension.
Gilead Sciences to Acquire Myogen, Inc. for $2.5 Billion by Business Wire
With the launch of Flolan commercial operations and with our
Myogen Reports 2006 Second Quarter Results by Business Wire
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