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Franche-Comté |
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Franche-ComtéRegion of eastern France; area 16,202 sq km/6,256 sq mi; population (1999 est) 1,117,100. Its administrative centre is Besançon, and it includes the départements of Doubs, Jura, Haute-Saône, and Territoire de Belfort (see Belfort, Territoire de). About 40% of the land is forested, especially in the mountainous Jura, where there is dairying, farming, and forestry; elsewhere there are engineering, automobile, and plastics industries. Besançon is the region's largest city and traditional centre for manufacturing (watches and precision instruments). Other chief towns include Montbéliard, the site of an automobile production complex, Lons-le-Saulier, Vesoul, Pontarlier, and Dôle, which had been capital of the historic region until 1676. HistoryOnce independent and ruled by its own count, it was disputed by France, Burgundy, Austria, and Spain from the 9th century until it became a French province under the Treaty of Nijmegen in 1678.
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| of Franche-Comte, France) compiles nine articles on the applications of nanotechnology in drug delivery, for researchers, students, and practitioners, with specific discussion of the properties of nanoparticles in their sustained drug release and therapeutic approaches for cancer, diabetes, Zhen); Universite de Franche-Comte, Besancon, France (P. He pointed to a study by a colleague at the University of Franche-Comte in eastern France that showed cardiovascular problems in mice and rats that were injected repeatedly with EPO in doses that would be a rough proportional equivalent to what an athlete might use. |
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