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interferon |
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interferonNaturally occurring cellular protein that makes up part of mammalian defences against viral disease. Three types (alpha, beta, and gamma) are produced by infected cells and enter the bloodstream and uninfected cells, making them immune to virus attack. Interferon was discovered in 1957 by Scottish virologist Alick Isaacs. Interferons are cytokines, small molecules that carry signals from one cell to another. They can be divided into two main types: type I (alpha, beta, tau, and omega) interferons are more effective at bolstering cells' ability to resist infection; type II (gamma) interferon is more important to the normal functioning of the immune system. Alpha interferon may be used to treat some cancers; interferon beta 1b has been found useful in the treatment of multiple sclerosis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Following stimulation of isolated lymphocytes, gamma interferon levels in the patient and his sister were normal at 113 and 293 U/mL respectively (done by Specialty Laboratories, Santa Monica, CA). Tuberculosis contacts but not patients have higher gamma interferon responses to ESAT-6 than do community controls in The Gambia. However, it is preparing for clinical trials in the use of Gamma Interferon antibodies to treat corneal transplant rejection later this year. |
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