graft-versus-host disease
| Complication of bone-marrow transplant where the grafted bone marrow attacks its host. In its mildest form patients develop a skin rash, but gut and liver inflammation can occur in more severe forms. |
| GVHD occurs in more than a third of patients receiving transplants from siblings. Its incidence is higher where donors are unrelated. Once established GHVD has a mortality rate of between 10 and 30%. |
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