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graft-versus-host disease
(redirected from Graft versus host disease)

   Also found in: Medical, Acronyms, Wikipedia 0.01 sec.

graft-versus-host disease

Complication of bone-marrow transplant where the grafted bone marrow attacks its host. In its mildest form patients develop a skin rash, but gut and liver inflammation can occur in more severe forms.

GVHD occurs in more than a third of patients receiving transplants from siblings. Its incidence is higher where donors are unrelated. Once established GHVD has a mortality rate of between 10 and 30%.



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? Mentioned in ? References in periodicals archive
 
In 50% of the patients who survive, Graft Versus Host Disease or delayed
Enzo said that its treatment of graft versus host disease was one of three therapeutic applications the company was preparing for clinical trials.
Osiris is eligible to receive up to $500 million in development and regulatory milestone payments for Prochymal related to graft versus host disease, Crohn's disease, and other potential additional indications that the companies develop together.
 
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