Heat-labile enterotoxin - Hutchinson encyclopedia article about Heat-labile enterotoxin Printer Friendly
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Escherichia coli
(redirected from Heat-labile enterotoxin)

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Escherichia coli

Rod-shaped Gram-negative bacterium (see bacteria) that lives, usually harmlessly, in the colon of most warm-blooded animals. It is the commonest cause of urinary tract infections in humans. It is sometimes found in water or meat where faecal contamination has occurred and can cause severe gastric problems.

The mapping of the genome of E. coli, consisting of 4,403 genes, was completed in 1997. It is probably the organism about which most molecular genetics is known, and is of pre-eminent importance in recombinant DNA research.

Classification

Escherichia coli is the only species in the bacterial family Enterobacteriaceae.

In April 1997, the US Centers for Disease Control and Prevention estimated that the commonest toxic Escherichia coli strain, 0157:H7, may be responsible for illness in at least 20,000 people in the USA each year.
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? Mentioned in ? References in periodicals archive
 
Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene.
Low-dose exposure and immunogenicity of transgenic maize expressing ... by Cunnick, Joan E. / Environmental Health Perspectives
coli strains from 430 patients were selected, and all were analyzed by a multiplex PCR (3) that detects the following pathogenic genes: heat-stable and heat-labile enterotoxins (st, lt) for ETEC, intimin (eaeA) and bundle-forming pilus (bfp) for EPEC, Shiga toxin 1 and 2 (stx1, stx2) and intimin (eaeA) for STEC, and invasion-associated loci (ia1) for EIEC.
Drug-resistant diarrheogenic Escherichia coli, Mexico by DuPont, Herbert L. / Emerging Infectious Diseases
Identification of a gene within a pathogenicity island of enterotoxigenic Escherichia coli H10407 required for maximal secretion of the heat-labile enterotoxin.
Single multiplex polymerase chain reaction to detect diverse loci ... by Estrada-Garcia, Teresa / Emerging Infectious Diseases
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