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histamine

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histamine

Inflammatory substance normally released in damaged tissues, which also accounts for many of the symptoms of allergy. It is an amine, C5H9N3. Substances that neutralize its activity are known as antihistamines. Histamine was first described in 1911 by British physiologist Henry Dale (1875–1968).



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The active ingredient of Higuard azelastine hydrochloride exhibits anti-allergic effects by inhibiting and releasing leukotriens and histamine that cause allergy, relieving allergic symptoms including rhinitis (sneezing, runny and stuffy nose) and skin problems (urticaria, eczema, etc).
In the present study, we show that the heavy metal cadmium and the pesticide endosulfan produce such effects through an interaction of specific cerebral histamine receptor subtypes in the teleost ornate wrasse (Thalassoma pavo).
Vitamin C supplementation (1,000 mg three times per day) reduced histamine levels in people with either high histamine levels or low blood levels of vitamin C.
 
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