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human papillomavirus |
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human papillomavirus
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In Professor Lorincz's Hybrid Capture test, samples are sent to a lab and analysed by automated instruments that detect the human papillomavirus ( Although cervical-cancer screening has improved significantly since the Food and Drug Administration's (FDA) approval of HPV DNA detections assays--the Hybrid Capture 2 assay (HC2) and the SPF10 assay, for the detection of carcinogenic HPV--with cytology for primary screening, carcinogenic HPV testing has one critical limitation: poor positive predictive value. The current study was undertaken to compare ProEx C immunocytochemical staining and the Hybrid Capture 2 hr-HPV DNA test (Digene Corporation, Gaithersburg, Md) in detecting high-grade cervical disease using liquidbased SurePath (Becton, Dickinson and Company, Franklin Lakes, NJ) cytologic specimens positive for ASC-US. |
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