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human papillomavirus
(redirected from Hybrid capture)

    Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.

human papillomavirus

Virus responsible for the common wart. It is one of a group of viruses implicated in tumour formation and is believed to play an important part in triggering cervical cancer that is the second most common cancer worldwide; it is also linked with cancer of the anus, which is very rare. Vaccines are being developed against HPV. A vaccine that protects from certain strains of HPV believed to cause the majority of cervical cancers became available in 2006.

From April 2007, the Australian government began offering this vaccine free of charge to all women aged 12 to 26.



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? Mentioned in ? References in periodicals archive
 
In Professor Lorincz's Hybrid Capture test, samples are sent to a lab and analysed by automated instruments that detect the human papillomavirus (
New virus test for cervical cancer 'cuts deaths by 50%' by The Evening Standard (London, England)
Although cervical-cancer screening has improved significantly since the Food and Drug Administration's (FDA) approval of HPV DNA detections assays--the Hybrid Capture 2 assay (HC2) and the SPF10 assay, for the detection of carcinogenic HPV--with cytology for primary screening, carcinogenic HPV testing has one critical limitation: poor positive predictive value.
HPV genotyping prior to vaccination holds promise by Kim, Jong-Kee / Medical Laboratory Observer
The current study was undertaken to compare ProEx C immunocytochemical staining and the Hybrid Capture 2 hr-HPV DNA test (Digene Corporation, Gaithersburg, Md) in detecting high-grade cervical disease using liquidbased SurePath (Becton, Dickinson and Company, Franklin Lakes, NJ) cytologic specimens positive for ASC-US.
ProEx C Immunocytochemistry and High-Risk Human Papillomavirus DNA ... by Momin T Siddiqui and Kelly Hornaman and Cynthia Cohen and Aziza Nassar / Archives of Pathology & Laboratory Medicine
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