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immunoglobulin |
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immunoglobulinHuman globulin protein that can be separated from blood and administered to confer immediate immunity on the recipient. It participates in the immune reaction as the antibody for a specific antigen (disease-causing agent). Normal immunoglobulin (gamma globulin) is the fraction of the blood serum that, in general, contains the most antibodies, and is obtained from plasma pooled from about a thousand donors. It is given for short-term (two to three months) protection when a person is at risk, mainly from hepatitis A (infectious hepatitis), or when a pregnant woman, not immunized against German measles, is exposed to the rubella virus. Specific immunoglobulins are injected when a susceptible (nonimmunized) person is at risk of infection from a potentially fatal disease, such as hepatitis B (serum hepatitis), rabies, or tetanus. These immunoglobulins are prepared from blood pooled from donors convalescing from the disease. |
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? Mentioned in | ? References in periodicals archive | |
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Health officials said they haven't found a reason to close the restaurant, but said anyone who might have eaten there since Thanksgiving should call their physician to receive immune globulin, the treatment for hepatitis A, to prevent possible disease. Encouraged by the therapy's modest success, Zuberi subsequently gave immune globulins to a teenage patient who'd had narcolepsy since she was a toddler. Passive administration of human botulinum immune globulin derived from volunteers vaccinated with pentavalent botulinum toxoid (ABCDE) vaccine has been protective in monkeys (19) and guinea pigs (20) against aerosolized botulinum toxin. |
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