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inflammation |
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inflammationDefensive reaction of the body tissues to disease or damage, including redness, swelling, and heat. Denoted by the suffix -itis (as in appendicitis), it may be acute or chronic, and may be accompanied by the formation of pus. This is an essential part of the healing process. Inflammation occurs when damaged cells release a substance (histamine) that causes blood vessels to widen and leak into the surrounding tissues. This phenomenon accounts for the redness, swelling, and heat. Pain is due partly to the pressure of swelling and also to irritation of nerve endings. Defensive white blood cells congregate within an area of inflammation to engulf and remove foreign matter and dead tissue. |
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| In Figure 1 the inflammatory response after 24 hr is expressed as the ratio of the polymorphonuclear leukocytes (PMNs) to lavaged cells, and the instilled dose is normalized to lung weight, because this facilitates interspecies comparison (Oberdorster et al. Consumption of a meal high in saturated fat typically causes an inflammatory response in the body that negatively impacts the ability of the arteries to carry necessary blood to tissue and organs and promotes the formation of artery clogging plaque. This is because such conditions are not reflected in a microscopic bacterial inflammatory response. |
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Inflammatory response
