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interferon
(redirected from interferon alpha)

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interferon

Naturally occurring cellular protein that makes up part of mammalian defences against viral disease. Three types (alpha, beta, and gamma) are produced by infected cells and enter the bloodstream and uninfected cells, making them immune to virus attack.

Interferon was discovered in 1957 by Scottish virologist Alick Isaacs. Interferons are cytokines, small molecules that carry signals from one cell to another. They can be divided into two main types: type I (alpha, beta, tau, and omega) interferons are more effective at bolstering cells' ability to resist infection; type II (gamma) interferon is more important to the normal functioning of the immune system. Alpha interferon may be used to treat some cancers; interferon beta 1b has been found useful in the treatment of multiple sclerosis.



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? Mentioned in ? References in periodicals archive
 
In patients with HCV, interferon alpha (IFN-[alpha]) has been reported as efficacious for the treatment of mixed cryoglobulinemia.
Regulation of interferon alpha responsiveness by the duration of Janus kinase activity.
Researchers at the University of Texas-Houston Health Science Center studied interferon alpha (related to the interferon betas used in MS) combined with Copaxone in lab mice with
 
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