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keratin |
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keratinFibrous protein found in the skin of vertebrates and also in hair, nails, claws, hooves, feathers, and the outer coating of horns. If pressure is put on some parts of the skin, more keratin is produced, forming thick calluses that protect the layers of skin beneath. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Cell lines derived from the tumors formed by injection of arsenite-exposed HaCaT cells into nude mice expressed higher levels of keratin 6, a proliferation marker of keratinocytes, than did parental HaCaT cells, whereas the expression of keratins 5, 8, and 10 was significantly decreased. The tumor cells were also positive for keratins (AE1/AE3 and 35BH11), but they were negative for melanoma-specific antigen (HMB45) and CD34 (QBEND/10). Keratinocytes produce keratins, proteins that help give skin its protective properties, says Dr. |
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