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L-dopa

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L-dopa

Chemical, normally produced by the body, which is converted by an enzyme to dopamine in the brain. It is essential for integrated movement of individual muscle groups.

L-dopa is a left-handed isomer of an amino acid C9H11NO2. As a treatment, it relieves the rigidity of Parkinson's disease in 60% of sufferers, but may have significant side effects, such as extreme mood changes, hallucinations, and uncontrolled writhing movements. It is often given in combination with other drugs to improve its effectiveness at lower doses.



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The research team, which included Dr Tamara Shiner and Professor Ray Dolan, examined estimated pleasure of future events before and after the administration of a drug called L-DOPA which is known to enhance dopamine function in the brain and is commonly used to treat patients with Parkinson's disease.
They were then given L-DOPA or a placebo and asked to imagine holidaying in those destinations.
Researchers are investigating if the drug L-dopa, alongside physiotherapy and occupational therapy, can boost stroke patients' mobility and increase their chances of walking again.
 
 
 
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