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scleroderma
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scleroderma

In medicine, condition characterized by thickening of the skin. This results in the skin becoming hard, the joints stiffening, and a gradual wasting of the muscles. It is thought to be caused by malfunctioning of the immune system.
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A report from Professor Radford Shanklin, of the University of Tennessee, one of the world's foremost experts on the dangers of silicone, said David was sadly showing all the classic early symptoms of scleraderma.
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