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tyrosine
(redirected from Tyrosine hydroxylase)

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tyrosine

One of the 20 amino acids found in proteins. It is important in the production of catecholamines, such as adrenaline, noradrenaline, and dopamine, which are involved in the transmission of nerve impulses. It is also important in the production of thyroid hormones, such as thyroxine.



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This allele predisposes one to increased tyrosine hydroxylase (TH) activity, and TH activity serves as a biochemical index of activity of noradrenergic neurons and the adrenal medulla.
Activated forms of pyridoxine, niacin, iron, and tetrahydrobiopterin are cofactors for the enzymes tyrosine hydroxylase and tryptophan 5-hydroxylase, which participate in brain biosynthesis of catecholamines and serotonin.
They contrasted the effects on cell viability, DNA synthesis associated with cell replication, and increased expression of enzyme markers that characterize cholinergic or catecholaminergic phenotypes: choline acetyltranferase (CHAT) and tyrosine hydroxylase (TH), respectively.
 
 
 
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