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tyrosine
(redirected from Tyrosines)

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tyrosine

One of the 20 amino acids found in proteins. It is important in the production of catecholamines, such as adrenaline, noradrenaline, and dopamine, which are involved in the transmission of nerve impulses. It is also important in the production of thyroid hormones, such as thyroxine.



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The tyrosines are iodinated at one (monoiodotyrosine) or two (diiodotyrosine) sites and then coupled to form the active thyroid hormones, tetraiodothyronine or thryoxine ([T.
This iodination of specific tyrosines on Tg yields monoiodinated and diiodinated residues [monoiodotyrosines (MITs) and diiodotyrosines (DITs)] that are enzymatically coupled to form [T.
The phosphorylation of tyrosines within the activation loop of rJAK2 appears to increase its autocatalytic efficiency with respect to ATP, with highest activity when its activation loop is phosphorylated and lower activity when the activation loop is unphosphorylated.
 
 
 
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