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volume
(redirected from Volume of distribution)

   Also found in: Dictionary/thesaurus, Medical, Legal, Financial, Acronyms, Encyclopedia, Wikipedia 0.07 sec.

volume

In geometry, the space occupied by a three-dimensional (3D) solid object. A prism such as a cube, cuboid, or a cylinder has a volume equal to the area of the base multiplied by the height. For a pyramid or cone, the volume is equal to one-third of the area of the base multiplied by the perpendicular height. The volume of a sphere is equal to 4/3 × πr3, where r is the radius. Volumes of irregular solids may be calculated by the technique of integration.



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? Mentioned in ? References in periodicals archive
 
Low concentrations are characteristic of chronic leiver disease, being due to both decreaswed synthesis and an increase in the volume of distribution as a result of fluid retention and the formation of ascites.
Therapeutics The hypothetical calculation of the volume of distribution in liters of unmetabolized drug cleared through the liver in 1 min–L/min.
Thyroid hormone is exten sively bound to plasma proteins, making the volume of distribution small and plasmapheresis a useful therapeutic modality.
 
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