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neurofibromatosis
(redirected from Von Recklinghausen disease)

   Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia 0.02 sec.

neurofibromatosis

Rare genetic disorder characterized by coffee-coloured spots or multiple soft skin swellings all over the body and by benign tumours of nerve sheaths (neurofibromas). It sometimes causes skeletal deformities. The gene responsible for the condition was discovered 1990 but there is still no cure (as of 2007).



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He had suffered from von Recklinghausen disease, as depicted in the film Elephant man, with huge benign tumours growing on the face.
Half of these tumors arise de novo, and the other half derive from nerves involved by neurofibroma as part of von Recklinghausen disease (neurofibromatosis type 1).
 
 
 
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