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acetanilide

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acetanilide

C6H5NHCOCH3, a crystalline substance obtained from the reaction between aniline and glacial acetic acid. Acetanilide was introduced into medicine 1886 as an antipyretic (fever-reducing drug); it also has analgesic (pain-relieving) properties. Overdosage leads to methaemoglobinaemia and the less toxic paracetamol is now preferred.
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Adams exposed how some headache powders, for instance, often sold by door-to-door salesmen, actually contained high levels of acetanilide, a toxic and addictive painkiller that caused heart attacks and kidney disease.
Scorin' with Orrin by MENCIMER, STEPHANIE / Washington Monthly
In particular, the contribution of CYP1A and NAT2 enzymes to the metabolism of aniline-derived xenobiotics such as acetanilide and phenacetin is well known (63).
Pharmacogenetic Profile of Xenobiotic Enzyme Metabolism in Survivors ... by Sanz, Emilio J. / Environmental Health Perspectives
The Acetanilide Pesticides: Alachlor, Metolachlor, and Acetochlor.
Comparative Metabolism of Chloroacetamide Herbicides and Selected ... by Rose, Randy L. / Environmental Health Perspectives
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