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acetyl coenzyme A
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acetyl coenzyme A

Compound active in processes of metabolism. It is a heat-stable coenzyme with an acetyl group (COCH3) attached by a sulphur linkage. This linkage is a high-energy bond and the acetyl group can easily be donated to other compounds. Acetyl groups donated in this way play an important part in glucose breakdown as well as in fatty acid and steroid synthesis. It is involved in the Krebs cycle, the cyclical pathway involved in the intracellular metabolism of foodstuffs.



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The free fatty acid, therefore, is attached to coenzyme-A by means of a thioester bond, catalyzed by means of the enzyme fatty acetyl-CoA synthetase.
Keywords: Sesquiterpene lactone; Anthecotulide; Anthemis auriculata; Plasmodium; Mycobacterium tuberculosis; Escherichia coli; Fatty acid biosynthesis; FabI Introduction Fatty acid (FA) biosynthesis is a metabolic pathway by which acetyl-CoA is converted into short to long chain FAs.
In aerobic respiration, acetyl-CoA is then channeled into the Krebs/citric acid cycle to create the reduced form of nicotinamide adenine dinucleotide (NADH).
 
 
 
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