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tolerance
(redirected from acquired tolerance)

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tolerance

In medicine, gradual increase of resistance to a drug's effects when it is taken over a long period. This means that more of the drug must be taken to achieve the desired effect.



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The Medawar Prize is named for Society co-founder Sir Peter Medawar, who received the Nobel Prize in Medicine in 1960 for his landmark studies on actively acquired tolerance to transplanted tissue.
Overexpression of glutathione S-transferase II and multidrug resistance transport proteins is associated with acquired tolerance to inorganic arsenic.
Acquired tolerances may turn new habits, such as alcohol, into addictions--which are fun to the affluent who can conceal them but are condemned when they cannot be concealed by the poor.
 
 
 
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