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interferon
(redirected from alpha-interferon)

   Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia 0.02 sec.

interferon

Naturally occurring cellular protein that makes up part of mammalian defences against viral disease. Three types (alpha, beta, and gamma) are produced by infected cells and enter the bloodstream and uninfected cells, making them immune to virus attack.

Interferon was discovered in 1957 by Scottish virologist Alick Isaacs. Interferons are cytokines, small molecules that carry signals from one cell to another. They can be divided into two main types: type I (alpha, beta, tau, and omega) interferons are more effective at bolstering cells' ability to resist infection; type II (gamma) interferon is more important to the normal functioning of the immune system. Alpha interferon may be used to treat some cancers; interferon beta 1b has been found useful in the treatment of multiple sclerosis.



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? Mentioned in ? References in periodicals archive
 
Starting cancer patients on an antidepressant before they begin receiving alpha-interferon markedly reduces the therapy's side effects, Miller and his colleagues now report.
Researchers at the Medical College of Cornell University discovered a deficiency in the production of alpha-interferon in women with VVS.
Food and Drug Administration (FDA) last week approved the marketing of bacterially manufactured human alpha-interferon, making it the first member of the interferon family to be commercially available in the United States.
 
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