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anticholinergic

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anticholinergic

Any drug that blocks the passage of certain nerve impulses in the central nervous system by inhibiting the production of acetylcholine, a neurotransmitter.

Its wide range of effects makes it an effective component of premedication before surgery; it may be put in the eyes before examination or treatment to dilate the pupil and paralyse the muscles of accommodation, or inhaled to relieve constriction of the airways in bronchitis. Tremor and rigidity can be reduced in mild Parkinson's disease. Bladder muscle tone may also be improved in the treatment of frequent urination. Its usefulness as an antispasmodic is limited by side effects, such as dry mouth, visual disturbances, and urinary retention.
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? Mentioned in ? References in periodicals archive
 
Antisialagogues are frequently used alone or in combination with other forms of therapy; these anticholinergic drugs act on the cholinergic, parasympathetic, secretomotor neurons of the gland and cause a temporary reduction in salivary output.
Parotid sialocele in a 10-year-old girl by Mitchell, Ron B. / Ear, Nose and Throat Journal
A French study has found the anticholinergic class of drugs, used in treating elderly patients, causes dementia-like symptoms.
Dementia-like symptoms by Australian Nursing Journal
A selective anticholinergic agent developed by Pfizer of the US, Detrusitol can exert beneficial effects with once-a-day dosage.
Pfizer Japan Obtains Approval for ZYVOX, Detrusitol, J Zoloft in Japan by JCNN News Summaries
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