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anticoagulant |
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anticoagulantSubstance that inhibits the formation of blood clots. Common anticoagulants are heparin, produced by the liver and some white blood cells, and derivatives of coumarin, such as warfarin. Anticoagulants are used medically in the prevention and treatment of thrombosis and heart attacks. Anticoagulant substances are also produced by blood-feeding animals, such as mosquitoes, leeches, and vampire bats, to keep the victim's blood flowing. Most anticoagulants prevent the production of thrombin, an enzyme that induces the formation from blood plasma of fibrinogen, to which blood platelets adhere and form clots. |
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Gradman said Medicare is pressing for clot prevention with the use of anticoagulant drugs such as heparin before surgeries, particularly procedures such as hip and knee replacements that are linked to a higher incidence of DVT. These patients risk a recurrence even if they've received treatment to dissolve the clot and have taken anticoagulant drugs for weeks or months. Since many elderly people require anticoagulant therapy, every nurse needs to be aware of the dosage, uses, contraindications, peak levels, precautions, and therapeutic lab values for anticoagulant drugs. |
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anticoagulant drugs
