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anticoagulant |
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anticoagulantSubstance that inhibits the formation of blood clots. Common anticoagulants are heparin, produced by the liver and some white blood cells, and derivatives of coumarin, such as warfarin. Anticoagulants are used medically in the prevention and treatment of thrombosis and heart attacks. Anticoagulant substances are also produced by blood-feeding animals, such as mosquitoes, leeches, and vampire bats, to keep the victim's blood flowing. Most anticoagulants prevent the production of thrombin, an enzyme that induces the formation from blood plasma of fibrinogen, to which blood platelets adhere and form clots. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Secondary to his worsening pulmonary condition and a lack of response to anticoagulation and antibiotic therapy, he was taken to the operating room for ligation of the right IJV. Four of the 236 enoxaparin-treated patients had dangerous bleeding after surgery, presumed to be caused by excessive anticoagulation. The laboratory data on admission indicated excessive anticoagulation with an international normalized ratio (INR) (20) of 5. |
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