Alcohol causes the brain, specifically the pituitary gland, to clock vasopressin, the body''s natural antidiuretic hormone.

When there is a large amount of urine produced at night by the kidney, a synthetic antidiuretic hormone medication called desmopressin can be prescribed to decrease the amount of urine produced.

The increase of % TBW could be the result of different mechanisms: Protein catabolism with hypoproteinemic edema, increased protein synthesis with increased plasma volume (PV), increase in PV due to sodium retention, based on an increased aldosterone concentration and impairment of the antidiuretic hormone and dehydration and impaired renal function due to skeletal muscle damage.