They also hypothesized that this "might predispose to platelet aggregation with formation of microthrombi atheromatous plaques" (Berry et al.

As well as including new content on syncope and pulmonary hypertension, major revisions cover the primary and secondary prevention of atheromatous disease, cardiovascular risk assessment tools, treatment of declining renal function, improving the prognosis of heart failure, coronary ischaemic syndromes, pre-eclampsia, uncomplicated essential hypertension and the assessment and treatment of smoking.

pneumoniae with atherosclerosis include seroepidemiologic studies, direct detection of bacterial components in atherosclerotic lesions, occasional isolation of viable organisms from coronary and carotid atheromatous tissue, and in vitro and animal experiments (reviewed in 8,9,13,14).