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peptide
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   Also found in: Dictionary/thesaurus, Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.

peptide

Molecule comprising two or more amino acid molecules (not necessarily different) joined by peptide bonds, whereby the acid group of one acid is linked to the amino group of the other (CO.NH). The number of amino acid molecules in the peptide is indicated by referring to it as a di-, tri-, or polypeptide (two, three, or many amino acids).

Proteins are built up of interacting polypeptide chains with various types of bonds occurring between the chains. Incomplete hydrolysis (splitting up) of a protein yields a mixture of peptides, examination of which helps to determine the sequence in which the amino acids occur within the protein.



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In addition, Cal Bio researchers are investigating the potential for nasal administration of such compounds as human growth hormone, atrial natriuretic peptide (used experimentally in the management of high blood pressure), cholecystokinin derivatives (useful as appetite suppressants) and hormonal analogs with potential in contraception and in the treatment of endometriosis (SN: 3/5/88, p.
Compugen has identified an alternative splicing event in the gene that codes for the protein precursor of two natriuretic peptide hormones: atrial natriuretic peptide (ANP) and Urodilatin.
Accepted for presentation at ENDO 2000 is, "Vascular endothelial growth factor (VEGF) and atrial natriuretic peptide (pro-ANP) in enhanced external counterpulsation", to be presented by Drs.
 
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