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vaccine
(redirected from attenuated vaccine)

   Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia 0.02 sec.

vaccine

Any preparation of modified pathogens (viruses or bacteria) that is introduced into the body, usually either orally or by a hypodermic syringe, to induce the specific antibody reaction that produces immunity against a particular disease.

In 1796 Edward Jenner was the first to inoculate a child successfully with cowpox virus to produce immunity to smallpox. His method, the application of an infective agent to an abraded skin surface, is still used in smallpox inoculation.



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Subsequent studies performed in children found no significant difference in shedding of attenuated vaccine strains in patients who had recovered from previous infection with a vaccine or natural strain of a different subtype than did study participants who had no evidence of previous virus exposure (15,16).
The major advantage is that vaccines generated using this delivery system are much safer than live attenuated vaccines and very cost effective for mass administration," Lamb said.
Nevertheless, some scientists haven't given up on a live attenuated vaccine.
 
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