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axon
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axon

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The anatomy and action of a nerve cell. The nerve cell or neuron consists of a cell body with the nucleus and projections called dendrites which pick up messages. An extension of the cell, the axon, connects one cell to the dendrites of the next. When a nerve cell is stimulated, waves of sodium (Na+) and potassium (K+) ions carry an electrical impulse down the axon.

Long threadlike extension of a nerve cell that conducts electrochemical impulses away from the cell body towards other nerve cells, or towards an effector organ such as a muscle. Axons terminate in synapses, junctions with other nerve cells, muscles, or glands.



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The authors also observed spherical axonal swellings and expanded motor end plates and postulated that spindle modifications may be the result of dennervation.
Histopathologic examination of sections from the cortex, hippocampus, thalamus, hypothalamus, midbrain, pons, medulla, and cerebellum showed polioencephalitis affecting predominantly the diencephalon and brainstem and involving varying degrees of neuronopathy, neuronal loss, astrocytosis, parenchymal and perivascular lymphocytic infiltration with CD45 immunopositivity, sparse macrophage activation, and axonal spheroid formation.
Uremia, ototoxins, axonal uremic neuropathy, anemia, and toxic degradation products from cellulose acetate dialyzer membranes are all possible etiologic factors.
 
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