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cataplexy

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cataplexy

Recurring condition in which there is a sudden loss of power throughout some or all of the voluntary muscles. It is sometimes triggered by an emotional stimulus, such as laughter or anger.

It usually occurs in association with narcolepsy.



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? Mentioned in ? References in periodicals archive
 
Cataplexy often occurs in response to strong emotions, such as surprise, anguish, or elation.
Even if clear-cut narcolepsy is present, per an incontrovertible history of cataplexy, overnight sleep laboratory monitoring usually still is warranted, due to the high prevalence of sleep apnea: even as an aggravating factor that could render treatment for narcolepsy less efficacious.
Xyrem has demonstrated an acceptable safety profile in narcoleptics with cataplexy when administered in nightly divided doses of 6 to 9 g with a recommended starting dose of 4.
 
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